MTHFR
MTHFR. That’s a mouthful to say, isn’t it? The acronym represents a gene that breaks down an enzyme called methylenetetrahydrofolate reductase, whose primary job is to help metabolize the B vitamin, folate, which is required to create healthy DNA. Recently medical science has begun to understand its role, importance, and the mutation that may occur within this gene that causes multiple health concerns.
What Exactly Does MTHFR Do?
At the heart of MTHFR’s significance lies its involvement in methylation, a crucial biochemical process that plays a pivotal role in various essential functions, including:
- DNA synthesis and repair
- Neurotransmitter production
- Hormone regulation
- Detoxification processes
Essentially, it serves as the master on/off switch for methyl synthesis in the body. For individuals with specific MTHFR gene variations, the body’s ability to convert folate to methylfolate is impaired. When this impairment occurs, it can lead to elevated levels of homocysteine, an amino acid whose excess can contribute to a multitude of health issues.
Normally homocysteine is used by the body to produce proteins, which are the building blocks of all cellular functions. Homocysteine levels should typically be low. When the MTHFR gene is functioning correctly, it breaks down B vitamins, including:
- B12 (cobalamin)
- B6 (pyridoxine)
- Vitamin B9 (folic acid, the synthetic form of folate)
very quickly so they can be used for a variety of functions in the body. However, when a MTHFR mutation is present, the body can’t process these B vitamins, especially B9, correctly, leading to an elevated homocysteine level.
An elevated homocysteine level, which can be the result of a MTHFR mutation, may be related to various medical conditions, including:
- Heart attacks
- Strokes
- Blood clots
- Depression
- Anxiety
- ADHD
- Alzheimer’s disease
- Pregnancy complications
- Increased risk of miscarriage
- Neural tube defects like spina bifida
- Digestive disorders
- Hormonal imbalances
- Chronic fatigue
- Pain
- Osteoporosis
- Thyroid
Needless to say, managing a MTHFR mutation is important – even critical – to your health and well-being.
Managing A MTHFR Mutation
Managing a MTHFR variation involves a multifaceted approach. Consuming foods rich in B vitamins, such as:
- Dark green leafy vegetables
- Chicken
- Asparagus
- Bananas
- Beans
- Beef
- Dairy products
can help support methylation processes. Additionally, stress management is paramount, as chronic stress can impede methylation. Practices like meditation, yoga, and deep breathing exercises can aid in reducing stress and promoting overall wellness.
Adopting certain lifestyle measures can further support health in the presence of a MTHFR variation. These may include:
- Eliminating smoking
- Minimizing alcohol consumption
- Eliminating processed foods
- Eating organic foods whenever possible
- Reducing inflammation
- Improving gut health
However, some individuals may require additional support if they experience persistent health issues or unexplained medical conditions. Treatments tailored to managing the effects of a MTHFR variation may include boosters of B-complex vitamins, B-12, or glutathione, either administered orally or intravenously.
The Wellness Connection Aesthetics & Health
The Wellness Connection Aesthetics & Health in Ellensburg, WA, can do genetic testing to determine whether you have a MTHFR or other genetic mutation and we can provide a support protocol for it. Contact us today so we can help you.
Disclaimer: The information contained here was not written by a medical doctor and is intended for informational purposes only. This is not a substitute for medical advice.
